By April 2008, she felt like skipping out on a taping with Cher and Tina Turner in Los Vegas. "I felt like a cow," Winfrey wrote in the January 2008 issue of "O" magazine. However, she didn't stop supporting the causes she holds dear. Oprah and 2004 Nobel Peace Prize winner, Wangari Maathai, left, from Kenya take part in a tree planting ceremony at the Oprah Winfrey Leadership Academy for Girls in Henley-On-Klip, South Africa, Tuesday, Nov. 25, 2008.
Oprah Winfrey attends the Alvin Ailey Dance Theatre's 50th Anniversary Opening Night Gala in New York on Wednesday, Dec. 3, 2008. That year, Oprah said her goal is no longer to be thin, but instead to be strong, healthy and fit. She had hoped to get started with her "Best Life Week" in January 2009.
Iyanla Vanzant, best-selling author, spiritual coach and star of OWN: Oprah Winfrey Network's critically acclaimed and award-winning series, "Iyanla Vanzant: Fix My Life" and one of the most popular teachers on "Oprah's Live Class," with Oprah Winfrey' at "The Life You Want Weekend" tour in Atlanta on Saturday, Sept. 6, 2014. (Akili-Casundria Ramsess/Special to the AJC)