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Ency. home > Disease > A > Acromegaly

Acromegaly

Overview | Symptoms | Treatment | Prevention

Alternative names:

Hyperpituitarism

Symptoms

enlarged hands

enlarged feet

widened fingers or toes due to skin overgrowth with swelling, redness, and pain

enlarged jaw (prognathism)

enlarged facial bones

thickening of the skin

enlarged sebaceous glands

excessive sweating

decreased muscle strength (weakness)

limited joint mobility

joint pain (hip pain, knee pain, ankle pain, foot pain, pain over the small joints of the foot, shoulder pain, elbow pain, wrist pain, hand pain, pain over the small joints of the hand, or pain in any other joint)

carpal tunnel syndrome

change in face appearance, developed over less than 1 year

widely spaced teeth

swelling of the bony areas around a joint

In infants and children, the anterior fontanel (frontal skull opening) can remain open for years.

Additional symptoms that may be associated with this disease:

Signs and Tests

The level of growth hormone is high
The level of IGF-1 (insulin-like growth factor 1) is high
A spine x-ray shows abnormal bone growth
A cranial MRI or cranial CT scan may show a pituitary tumor

This disease may also alter the results of the following tests:

fasting plasma glucose (high)
glucose tolerance test (too high at 2 hours)
creatinine
creatinine - urine
17-ketosteroids
17-hydroxycorticosteroids

Ency. home > Disease > A > Acromegaly

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