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Ency. home > Disease > F > Factor X deficiency

Factor X deficiency   

Overview | Symptoms | Treatment | Prevention

Alternative names:

Stuart-Prower deficiency

Definition:

Factor X deficiency is an inherited disorder that causes abnormal blood clotting (coagulation), resulting from a deficiency of the plasma protein Factor X.

Causes and Risks

Normal blood coagulation is a complex process involving as many as 20 different plasma proteins, which are known as blood coagulation factors. A series of complex chemical reactions using these factors takes place very rapidly to form an insoluble protein called fibrin that stops bleeding.

When certain coagulation factors are deficient or missing, the chain reaction does not take place normally. Factor X deficiency is caused by an inherited defect of the Factor X gene, and bleeding ranges from mild to severe.

Women may have severe menstrual bleeding and bleeding after delivery. The incidence is 1 out of 500,000. Newborns may have prolonged bleeding after circumcision.

Ency. home > Disease > F > Factor X deficiency

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