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Ency. home > Disease > S > Secondary parkinsonism

Secondary parkinsonism   

Overview | Symptoms | Treatment | Prevention

Alternative names:

Parkinsonism - secondary

Definition:

Secondary parkinsonism is a disorder similar to Parkinson's disease, but is caused by the effects of a medication, a neurodegenerative disorder, or another illness.

Causes and Risks

Parkinson's disease is one of the most common neurologic disorders of the elderly. The term "parkinsonism" refers to any condition that causes any combination of the types of movement abnormalities seen in Parkinson's disease.

Secondary parkinsonism may be caused by disorders such as a stroke, encephalitis, or meningitis. Other neurodegenerative disorders such as progressive supranuclear palsy, corticobasal degeneration, and multiple systems atrophy.

Medications including tranquilizers (such as haloperidol), metoclopramide, and phenothiazine medications; exposure to narcotics or anesthesia agents (such as for surgery); exposure to toxins, carbon monoxide poisoning, recreational use of MPTP or other drugs (a common cause in adolescents); or it may occasionally be caused by other conditions.

Secondary parkinsonism caused by medications is usually reversible. If it is caused by toxins, infections, or disorders it may or may not be reversible.

Parkinsonism causes abnormality of movements due to dysreguation of neurotransmitters in the brain. The most common abnormality is in dopamine. This may result in stiffness of the trunk, arms or legs, a decrease in facial expression, tremor as well as other symptoms.

Although cognitive dysfunction is not a major feature of Parkinson's disease, it may be more prominent in secondary parkinsonism as the diseases that cause secondary parkinsonism more commonly also result in dementia.

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