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Ency. home > Disease > P > Progressive supranuclear palsy

Progressive supranuclear palsy

Overview | Symptoms | Treatment | Prevention

Alternative names:

Dementia-nuchal dystonia; Richardson-Steele-Olszewski syndrome; Palsy - progressive supranuclear

Symptoms

Repeated falls

Loss of coordination, unsteady gait (walking pattern)

Stiffness and rigid movement in the neck, trunk, arms, legs

Difficulty swallowing

May have a tremor

Pain or difficulty with bending the neck up or down

Slow or stiff movements

Vision difficulty

Unable to look up or down without bending the neck

Changes in facial expression

"Masking", reduced expression
Deeply lined face
Jaw or face jerks or spasms
Eyes, pupils different size
Eye movements, uncontrollable

Generalized slowness of all movement (bradykinesia) with strength relatively preserved

Speech difficulties

Slow speech
Poor enunciation
Low voice volume

Dementia, mild

Forgetfulness
Slowed thought processes
Apathy (indifference)
Difficulty manipulating knowledge

Personality changes, vague and mild

Signs and Tests

A neurological examination may show Parkinsonian movements with typical stiffness and lack of coordination. Dementia is mild. Eye movements are limited, particularly vertical movements. However, vision, hearing, sensation, and voluntary control of movement remains intact.

Tests may be done to rule out other diseases. An MRI might show shrinking of the brainstem.

Ency. home > Disease > P > Progressive supranuclear palsy

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