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Cold knife cone biopsy    See images

Overview | Risks | Results

Alternative names:

Cone biopsy; Biopsy - cone; Cervical conization

Definition:

A procedure to obtain a sample of abnormal tissue from the cervix for further examination. This procedure obtains a larger sample than that obtained by cervical punch biopsy or colposcopy-directed biopsy.

How the Test is Performed

This is a surgical procedure, performed in the hospital under either intravenous sedation or general anesthesia, to diagnose and treat a precancerous change in the cervix. A small cone-shaped sample of tissue is removed from the cervix and examined under a microscope for any signs of cancer. This biopsy may serve as the treatment, as well, if all of the diseased tissue is removed.

How to Prepare for the Test

As with any procedure performed under anesthesia, fasting for 6 to 8 hours is recommended. You must sign an informed consent form.  The procedure is considered as a same day procedure in which hospitalization is usually not necessary.

How the Test will Feel

After the procedure, there may be some cramping or discomfort for a week or so. Avoid sexual intercourse, douching, and use of tampons, for about 4 to 6 weeks. For 2 to 3 weeks after the procedure, you may have heavy, bloody or a yellow-colored discharge.

Why the Test is Performed

The test is done when results of a cervical biopsy indicate precancerous cells in the area or cervical cancer. A cold knife biopsy may also be done if the cervical biopsy has not revealed the cause of an abnormal pap smear.

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