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Ency. home > Test > B > Bone marrow biopsy

Bone marrow biopsy    See images

Overview | Risks | Results

Alternative names:

Biopsy - bone marrow

Definition:

The bone marrow is a soft tissue that is inside some of the larger bones. The bone marrow produces the red and white blood cells, and platelets (helps the blood to clot). A biopsy is a method of removing a small tissue sample from the body to have it examined under a microscope and possibly analyzed by other tests.

How the Test is Performed

The bone marrow biopsy may be done in the health care provider's office or in a hospital. The sample is usually taken from the hip bone. The skin is cleansed, and a local anesthetic is injected to numb the skin.

The biopsy needle is then inserted into the bone. The core of the needle will then be removed, and the needle is pressed forward and rotated in both directions. This forces a tiny sample of the bone marrow into the needle. The needle is then removed. Pressure is applied to the biopsy site to stop bleeding, and a bandage is applied. 

An aspirate may also be performed, usually before the biopsy is taken. After the skin is anesthetized, the aspirate needle is inserted into the bone, and a syringe is used to withdraw the liquid bone marrow. If this is performed, the needle will be removed and either repositioned, or another needle may be used for the biopsy.

How to Prepare for the Test

Inform the health care provider if you have allergies to any medications, about which medications you are taking, and if you have bleeding problems. The health care provider should also know if you are pregnant. You must sign a consent form.

Infants and children:
The physical and psychological preparation you can provide for this or any test or procedure depends on your child's age, interests, previous experiences, and level of trust. For specific information regarding how you can prepare your child, see the following topics as they correspond to your child's age:

How the Test will Feel

There will be a sharp stinging from the anesthetic injection. As the aspirate is withdrawn, there may be a brief, sharp pain. The biopsy needle may also produce a brief pain, usually more dull. Since the interior of the bone cannot be anesthetized, this test may cause some discomfort. Not all patients experience these symptoms, however.

Why the Test is Performed

The test is done after abnormal types or numbers of red or white blood cells are found in a complete blood count, or to evaluate whether other systemic diseases are present in the bone marrow.

The examination may detect the cause of the abnormality, certain types of anemia (not enough red blood cells), cancer in the marrow, and may be used to monitor the response to therapy for some cancers.

Ency. home > Test > B > Bone marrow biopsy

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