There's not that much difference in the initial plot happenings between Patrick Dempsey's "Made of Honor" and Julia Roberts' "My Best Friend's Wedding." (Other than he's a he and she's a she.) Really, there's not. Not much space between the stars, either.

Here's what connects Dempsey to Roberts:

Peter Iovino (ENLARGE)
Other than gender, the initial plot of Patrick Dempsey's 'Made of Honor' differs very little from 'My Best Friend's Wedding.'
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1. Patrick Dempsey stars in "Made of Honor" (opens May 2).

2. Dempsey co-starred with Reese Witherspoon in "Sweet Home Alabama" (2002).

3. Witherspoon co-starred with Meryl Streep in "Rendition" (2007).

4. Streep co-starred with Tom Cruise in "Lions for Lambs" (2007).

5. Cruise co-starred with Cameron Diaz in "Vanilla Sky" (2001).

6. Diaz co-starred with Julia Roberts in "My Best Friend's Wedding" (1997).

— Bob Longino